The win was the ninth in the last 10 home starts for the Knights.
UCF (7-3), which started its streak by beating No. 24 Alabama, led by two at intermission on a layup by A.J. Davis with :14 left, but trailed through most of second half.
Fall knocked down two free throws with 5:17 left in the game to put UCF in front for good, 50-49 while the defense limited the Lions to one field goal the rest of the way. Terrell Allen knocked down a jumper, scored on a layup and went 4-for-4 from the line in the final two minutes to put the game away.
James Currington and Marlain Veal each scored 10 points for Southeastern Louisiana (5-4).
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